It’s easy to think of medical tests as black and white. If the test is positive, you have the disease; if it’s negative, you don’t. Even good clinicians sometimes fall into that trap. Based on the pre-test probability of the disease, a positive test result only increases the probability by… read more "Screening Tests – Cumulative Incidence of False Positives"
Tactless About TACT: Critiques Without Substance Should Be Abandoned
In May 2008, the article “Why the NIH Trial to Assess Chelation Therapy (TACT) Should Be Abandoned” was published online in the Medscape Journal of Medicine. The authors included two of our own SBM bloggers, Kimball Atwood and Wallace Sampson, along with Elizabeth Woeckner and Robert Baratz. It showed that… read more "Tactless About TACT: Critiques Without Substance Should Be Abandoned"
Science under Siege
A new book, Science Under Siege: Defending Science, Exposing Pseudoscience addresses many of the issues near and dear to the hearts of SBM bloggers and readers. A compilation of some of the best writing from the last few years of Skeptical Inquirer magazine, it’s not only good reading but can… read more "Science under Siege"
AA is Faith-Based, Not Evidence-Based
Alcoholics Anonymous is the most widely used treatment for alcoholism. It is mandated by the courts, accepted by mainstream medicine, and required by insurance companies. AA is generally assumed to be the most effective treatment for alcoholism, or at least “an” effective treatment. That assumption is wrong. We hear about… read more "AA is Faith-Based, Not Evidence-Based"
Re-evaluating Home Monitoring for Diabetes: Science-Based Medicine at Work
There is no question that patients on insulin benefit from home monitoring. They need to adjust their insulin dose based on their blood glucose readings to avoid ketoacidosis or insulin shock. But what about patients with non-insulin dependent diabetes, those who are being treated with diet and lifestyle changes or… read more "Re-evaluating Home Monitoring for Diabetes: Science-Based Medicine at Work"
Chiropractic in the News
Three recent news items about chiropractic have particularly irritated me. (1) U.S. Army Brigadier General Becky Halstead (Retired) Speaks Out for Chiropractic Care(2) Chiropractic Helps Child with Brain Disorder(3) Swine Flu Chiropractor’s Handout (1) General Halstead has become a spokesperson for The Foundation for Chiropractic Progress, a nonprofit organization dedicated… read more "Chiropractic in the News"
Acupuncture for IVF Revisited – More Tooth Fairy Science?
I read this Reuters Health article on MedlinePlus, and then I read the study the article referred to (The impact of acupuncture on in vitro fertilization) and now my head hurts. The study found that acupuncture was not effective in increasing the pregnancy rate (PR) during in vitro fertilization (IVF). As quoted… read more "Acupuncture for IVF Revisited – More Tooth Fairy Science?"
Is IV Sedation Over-Used?
We criticize alternative medicine for not being evidence-based, and they criticize conventional medicine in turn, saying that much of what conventional medicine does is not based on evidence either. Sometimes that criticism is justified. I have run across a conventional practice that I suspect began because it sounded like a… read more "Is IV Sedation Over-Used?"
Evolutionary Medicine
I have been asked to review a pre-publication proof of a book that will be published in May 2009: Evolution Rx: A Physician’s Guide to Harnessing Our Innate Capacity for Health and Healing by William Meller, MD. It offers “a primal yet radical new view of why we act and… read more "Evolutionary Medicine"
PSA – To Screen or Not to Screen
You’ve all heard the dramatic testimonials in the media: “I had a PSA test and they found my prostate cancer early enough to treat it. The test saved my life. You should get tested too.” The subject of screening tests is one that confuses the public. On the surface, it… read more "PSA – To Screen or Not to Screen"