Flu shots are safe and effective. They not only protect the recipient but others in the community who are more vulnerable. Get your flu shot! It’s that time of the year again: time to get our flu shots. Flu shots are undeniably safe and effective, although they are not as… read more "Flu Shots: It’s That Time Again"
Estrogen Matters
Hormone replacement therapy in menopause is safer and more effective than we have been led to believe. A new book examines the evidence and sets the record straight. Estrogen replacement stops hot flashes cold and is a veritable Fountain of Youth. Estrogen replacement is dangerous: it kills women. It prevents… read more "Estrogen Matters"
Smoking Cessation
Smoking is the leading cause of preventable disease and death. There are effective pharmacological and non-pharmacological methods to help people stop smoking. Conventional medicine is often accused of ignoring prevention, just letting preventable diseases develop, and then only treating symptoms. And the Science-Based Medicine blog is often accused of ignoring… read more "Smoking Cessation"
Do Sunscreens Cause Cancer?
The diagnostic characteristics of melanoma A reader asked me to look into the claims that sunscreens cause cancer, especially the claims made by Elizabeth Plourde. When our own Scott Gavura evaluated sunscreens, he concluded: The data on sunscreen use and cancer risk are complex, but on balance suggest that the… read more "Do Sunscreens Cause Cancer?"
Cholesterol-shmesterol
Lewis Jones’ article “Cholesterol-shmesterol” is so full of distortions I hardly know where to start. He confuses the dietary cholesterol-heart connection with the blood cholesterol-heart connection, fails to differentiate between primary prevention (in healthy people) and secondary prevention (in those who already have heart disease), and he refers to “good”… read more "Cholesterol-shmesterol"
Announcing: Video Lecture Course on Science-Based Medicine
A couple of years ago, the James Randi Educational Foundation commissioned me to develop a series of 10 video lectures on Science-Based Medicine. After a lot of work and many vicissitudes, it is now available. The lecture titles are: Science-Based Medicine vs. Evidence-Based Medicine What Is CAM? Chiropractic Acupuncture Homeopathy Naturopathy and… read more "Announcing: Video Lecture Course on Science-Based Medicine"
The Debate Is Over: Antidepressants DO Work Better Than Placebo
Depression can kill. Antidepressants can help. A meme that continues to appear regularly in the media and in the comments section of this blog is “antidepressants are no better than placebo.” It is a false belief based on a faulty interpretation of the evidence. A new study has just… read more "The Debate Is Over: Antidepressants DO Work Better Than Placebo"
The Elephant in the Compounding Pharmacy
Compounding pharmacies create medicines specifically designed for the needs of an individual patient when those needs are not met by products available on the market. They may eliminate an ingredient the patient is allergic to, they may prepare a liquid version of a pill for patients who have difficulty swallowing,… read more "The Elephant in the Compounding Pharmacy"
The Movie “Cholesterol: The Great Bluff” Is an Exercise in Denialism
The movie “Cholesterol: The Great Bluff” claims that we have been lied to: cholesterol doesn’t cause heart disease and statins are harmful. It is biased and misleading. The people interviewed in the movie are denialists who don’t accept the clear evidence for the role of blood cholesterol levels and the… read more "The Movie “Cholesterol: The Great Bluff” Is an Exercise in Denialism"
“New vaccine replaces statins?” Not so fast!
News reports suggest new drugs may replace statins. PSCK9 inhibitors are useful, but only along with statins in high risk patients not controlled on statins alone, or for patients who can’t tolerate statins. They’re not about to replace statins. PyMOL rendering of the structure of the PCSK9 protein. Are statins obsolete? Are… read more "“New vaccine replaces statins?” Not so fast!"