A new stool DNA test was recently approved by the FDA for colon cancer screening. My first reaction was “Yay! I hope it’s good enough to replace all those unpleasant, expensive screening colonoscopies.” But of course, things are never that simple. I wanted to explain the new test for our… read more "Recent Developments and Recurring Dilemmas in Cancer Screening: Colon, Lung, Thyroid"
An Egregious Example of Ordering Unnecessary Tests
Last week I wrote about doctors who order unnecessary tests, and the excuses they give. Then I ran across an example that positively flabbered my gaster. A friend’s 21-year-old son went to a board-certified family physician for a routine physical. This young man is healthy, has no complaints, has no past… read more "An Egregious Example of Ordering Unnecessary Tests "
Why Doctors Order Too Many Tests
While cleaning out some old files, I was delighted to find an article I had clipped and saved 35 years ago: a “Sounding Boards” article from the January 25, 1979 issue of The New England Journal of Medicine. It was written by Joseph E. Hardison, MD, from the Emory University School of Medicine;… read more "Why Doctors Order Too Many Tests"
Precision Medicine: The Coolest Part of Medicine
One size rarely fits all. Most medical knowledge is derived from studying groups of subjects, subjects who may be different in some way from the individual who walks into the doctor’s office. Basing medicine only on randomized controlled studies can lead to over-simplified “cookbook” medicine. A good clinician interprets study… read more "Precision Medicine: The Coolest Part of Medicine"
Point-of-Care Ultrasound: The Best Thing Since Stethoscopes?
A bit of good news for a change: a “Perspective” article in the New England Journal of Medicine describes how point-of-care ultrasound devices are being integrated into medical education. The wonders of modern medical technology are akin to science fiction. We don’t yet have a tricorder like “Bones” McCoy uses on Star Trek,… read more "Point-of-Care Ultrasound: The Best Thing Since Stethoscopes?"
Colonoscopy and Other Colorectal Cancer Screening Options: An Update
When I wrote about colonoscopy in 2010, colonoscopy was thought to be the best screening test for colorectal cancer because it could visualize the entire colon and could remove adenomas that were precursors of cancer. But only fecal occult blood testing (FOBT) and sigmoidoscopy had been proven to decrease colorectal cancer incidence… read more "Colonoscopy and Other Colorectal Cancer Screening Options: An Update"
Baby’s DNA in Mom’s Blood: Noninvasive Prenatal Testing
Until recently, the moment of birth was a surprise. We anxiously awaited the obstetrician’s announcement: “It’s a boy!” or “It’s a girl!” Then we checked to see if any crucial parts were missing and we counted the fingers and toes. We had to wait for a baby to be born… read more "Baby’s DNA in Mom’s Blood: Noninvasive Prenatal Testing"
Does Everybody Have Chronic Lyme Disease? Does Anyone?
Borrelia burgdorferi, the Lyme spirochete, the bacteria that causes Lyme disease (but not chronic Lyme disease). A deplorable article by Suzy Cohen on Huffington Post is titled “Feel Bad? It Could Be Lyme Unless Proven Otherwise.” It consists of irresponsible fear-mongering about a nonexistent disease. A science-based article would be titled “Feel… read more "Does Everybody Have Chronic Lyme Disease? Does Anyone?"
A Skeptical Look at Screening Tests
I’m going to follow Mark Crislip’s example and recycle my presentation from The Amazing Meeting last week, not because I’m lazy or short on time (although I am both), but because I think the information is worth sharing with a larger audience. We’ve all had screening tests and we’re all likely… read more "A Skeptical Look at Screening Tests"
Meet Your Microbes: uBiome Offers New Service
We are not alone. Walt Whitman didn’t know how right he was when he said, “I contain multitudes.” The microbes on and in our bodies outnumber our own cells 10:1. Perhaps that creeps you out. Perhaps that makes you curious to know just who all these billions of creatures are… read more "Meet Your Microbes: uBiome Offers New Service"