When Dr. Novella recently wrote about plausibility in science-based medicine, one of our most assiduous commenters, Daedalus2u, added a very important point. The data are always right, but the explanations may be wrong. The idea of treating ulcers with antibiotics was not incompatible with any of the data about ulcers;… read more "Diagnosis, Therapy and Evidence"
Halsted: The Father of Science-Based Surgery
One (dark and stormy?) night in 1882, a critically ill 70 year old woman was at the verge of death at her daughter’s home, suffering from fever, crippling pain, nausea, and an inflamed abdominal mass. At 2 AM, a courageous surgeon put her on the kitchen table and performed the… read more "Halsted: The Father of Science-Based Surgery"
Time to Care: Personal Medicine in the Age of Technology
In 1925, Francis Peabody famously said “The secret of the care of the patient is in caring for the patient.” A new book by Norman Makous, MD, a cardiologist who has practiced for 60 years, is a cogent reminder of that principle. In Time to Care: Personal Medicine in the… read more "Time to Care: Personal Medicine in the Age of Technology"
Science in the Spirit of Mythbusters
We skeptics spend a lot of time critiquing non-science and too little time promoting science itself. Science is awe-inspiring and fun, and any effort to communicate that to our children is worthwhile. A new book by Sean Connolly, The Book of Potentially Catastrophic Science: 50 Experiments for Daring Young Scientists,… read more "Science in the Spirit of Mythbusters"
The Mythbusters of Psychology
Karl Popper said “Science must begin with myths and with the criticism of myths.” Popular psychology is a prolific source of myths. It has produced widely held beliefs that “everyone knows are true” but that are contradicted by psychological research. A new book does an excellent job of mythbusting: 50… read more "The Mythbusters of Psychology"
All Medicines Are Poison!
That’s the title of a new book by Melvin H. Kirschner, M.D. When I first saw the title, I expected a polemic against conventional medicine. The first line of the Preface reassured me: “Everything we do has a risk-benefit ratio.” Dr. Kirschner took the title from his first pharmacology lecture… read more "All Medicines Are Poison!"
Military Medicine in Iraq
Doctors get a lot of flak these days without ever going near a battle zone. They are bombarded with accusations of not caring about their patients, of being shills for Big Pharma, of being motivated by money, of killing patients with medical errors and drug side effects. In addition, they… read more "Military Medicine in Iraq"
Science-Based Medicine Meets Medical Ethics
There are four main principles in medical ethics: Autonomy Beneficence Non-maleficence Justice Autonomy means the patient has the right to consent to treatment or to reject it. Autonomy has to be balanced against the good of society. What if a patient’s rejection of treatment or quarantine allows an epidemic to… read more "Science-Based Medicine Meets Medical Ethics"
Incorporating Placebos into Mainstream Medicine
Alternative medicine by definition is medicine that has not been shown to work any better than placebo. Patients think they are helped by alternative medicine. Placebos, by definition, do “please” patients. We would all like to please our patients, but we don’t want to lie to them. Is there a… read more "Incorporating Placebos into Mainstream Medicine"
Birth Day
So many of the posts on this blog are critical and deal with examples of poor science or other problems. I’d like to offer a breath of fresh air in the form of a book by Mark Sloan, MD: Birth Day: A Pediatrician Explores the Science, the History, and the… read more "Birth Day"