For years, we have been told that most adults should take a baby aspirin every day to help prevent heart attacks and strokes. Now we are told not to do that because it doesn’t work. What is going on? Why can’t science make up its mind? The recommendations are not… read more "Does a Baby Aspirin a Day Keep the Doctor Away?"
Announcing a New Children’s Book that Promotes Critical Thinking
A new book teaches young children about critical thinking and evidence. It’s not only educational but colorful and funny. Too many adults are like Henry, the little boy in the story who rejects clear evidence and persists in what he wants to believe. Back in 2006 I wrote an article for Skeptical… read more "Announcing a New Children’s Book that Promotes Critical Thinking"
A Desperate Choice
A therapy for brain tumors in young children involves deliberately infecting them with a virus. Scary, and is it worth it? In a recent article in the New England Journal of Medicine I read about a novel possibility for treating cancer that I had not been aware of. The study’s title was “Oncolytic DNX-2401… read more "A Desperate Choice"
100% Cure Rate Is Hard to Believe
An experimental cancer drug made 100% of rectal cancers disappear in a small trial, allowing subjects to avoid the standard treatment of chemotherapy and surgery . “Some scientists say these kinds of results have never been seen in the history of cancer research.” 100% is hard to believe; the 95% confidence interval was 74… read more "100% Cure Rate Is Hard to Believe"
Statistical Shenanigans?
The manufacturers of Covid-19 vaccines say they are 95% effective. Peter Doshi re-examined the evidence and estimates they are only 19-29% effective. This pre-print of an as-yet unpublished re-analysis raises many questions but doesn’t support the claims being made on antivaccine sites. A correspondent asked for my opinion about a study that… read more "Statistical Shenanigans?"
The Role of Liquid Biopsies in Oncology
Liquid biopsies can be used to reduce the amount of chemotherapy used for patients with stage II colon cancer. When a patient has cancer, cell-free tumor DNA circulates in the blood and can be detected in a peripheral blood sample. This is known as a “liquid biopsy,” and it has… read more "The Role of Liquid Biopsies in Oncology"
Will Intermittent Fasting Help You Lose Weight?
Are you having trouble losing weight? So are a lot of other people. Have you tried intermittent fasting? Should you? According to a survey by the International Food Information Council, intermittent fasting was the most popular weight loss diet in 2018. Some have called it a fad whose adverse effects have… read more "Will Intermittent Fasting Help You Lose Weight?"
Diet Recommendations Based on DNA
Diet recommendations based on DNA are not based on good science. When the human genome was first sequenced, some people optimistically assumed that we now knew (or soon would know) everything about human genetics and would be able to predict who would develop a disease and prescribe what each individual… read more "Diet Recommendations Based on DNA"
Medical Tests to Avoid
When I first started looking into chiropractic, I read about one of their continuing medical education (CME) offerings. CME for physicians is intended to update their knowledge so they can treat patients more effectively. This chiropractic CME course didn’t try to inform chiropractors about new knowledge from recent studies (there… read more "Medical Tests to Avoid"
Chiropractic Neck Manipulations in the News
Caitlin Jensen’s chiropractor called 911 when she developed alarming symptoms after neck manipulation. She had a heart attack, was pulseless for 10 minutes, and suffered traumatic brain injury. Surgeons found dissections of 4 arteries in the neck. A month later, she remains paralyzed and is still in the ICU. I’ve… read more "Chiropractic Neck Manipulations in the News"